Treating Depression with Selective Serotonin Reuptake Inhibitors

Selective Serotonin Reuptake Inhibitors (SSRIs) are a class of medications that are commonly used to treat depression. SSRIs work by increasing the levels of serotonin, a neurotransmitter that is associated with mood regulation, in the brain.

SSRIs are usually well-tolerated and have fewer side effects compared to other classes of antidepressants. Common SSRIs include fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa), escitalopram (Lexapro), and paroxetine (Paxil).

SSRIs may take several weeks to start working, and it is important to take them as directed by a healthcare professional. It is also important to continue taking them even if symptoms improve, as abruptly stopping SSRIs can lead to withdrawal symptoms.

Some common side effects of SSRIs include nausea, diarrhea, headache, dizziness, and difficulty sleeping. Sexual dysfunction, such as decreased libido or difficulty achieving orgasm, is also a potential side effect.

In rare cases, SSRIs can cause serotonin syndrome, a potentially life-threatening condition that occurs when serotonin levels become too high in the body. Symptoms of serotonin syndrome include agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, muscle rigidity, and fever.

It is important to talk to a healthcare professional about any potential side effects of SSRIs and to report any adverse effects immediately.