The Gastrointestinal Bleeding Risk Associated with Aspirin Use for Heart Disease and Colorectal Cancer

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for the prevention of heart disease and stroke. It is also recommended as a preventive measure for colorectal cancer in some high-risk individuals. However, aspirin use can increase the risk of gastrointestinal (GI) bleeding, including bleeding from the stomach and intestines.

Studies have shown that aspirin use is associated with an increased risk of GI bleeding, particularly in elderly patients and those with a history of GI bleeding. The risk is also higher in those who take higher doses of aspirin and those who take it for longer periods of time.

To reduce the risk of GI bleeding associated with aspirin use, it is recommended that patients take the lowest effective dose for the shortest possible time. Patients with a history of GI bleeding or ulcers should talk to their doctor before taking aspirin, and in some cases, an alternative medication may be recommended. Additionally, taking aspirin with food or a stomach protectant medication may also reduce the risk of GI bleeding.

It’s important for individuals to discuss the risks and benefits of aspirin use with their healthcare provider to determine the best course of treatment for their specific needs.